The Five Best Terpenes to Enhance Sleep Quality
We discuss the five best terpenes to enhance sleep quality due to a widespread issue of insomnia - over 50% of Brits suffer from lack of sleep.
Struggling with insomnia is a widespread issue, as previously discussed in our blog post. Mamedica’s research indicates that 51% of Brits experience sleep difficulties and choose to avoid prescription drugs due to groggy side effects, prompting many to seek natural remedies for relief. Among these, terpenes found in medicinal cannabis are showing promise for enhancing sleep quality.
Understanding Terpenes
Terpenes are organic compounds produced by various plants, including cannabis. These compounds are responsible for the distinct aromas and flavours of different cannabis strains. Beyond their sensory characteristics, terpenes possess therapeutic properties that can influence mood, energy levels, and overall health. These compounds engage with the endocannabinoid system, a complex signalling system in our bodies, to regulate and enhance sleep quality. Here, we highlight five terpenes with sleep-supporting properties and provide insights into how they can improve your sleep.
1. Myrcene: A Natural Sedative
Myrcene is one of the most prevalent terpenes in cannabis and is recognised for its sedative effects. It emits a musky, earthy aroma with clove-like undertones and is commonly found in strains such as Granddaddy Purple and OG Kush.
Effects on Sleep: Myrcene promotes muscle relaxation and a sense of calm by interacting with the body’s endocannabinoid system to enhance the sedative properties of THC, leading to a more pronounced feeling of relaxation. Its sedative properties can aid in falling asleep faster and achieving deeper, more restorative sleep. Additionally, myrcene is believed to have pain-relief properties, which can further contribute to a better night’s sleep by alleviating discomfort.
2. Linalool: Calming and Soothing
Linalool, known for its calming effects, has a sweet, floral scent similar to lavender. This terpene is also found in strains like Amnesia Haze and Lavender.
Effects on Sleep: Linalool can reduce anxiety by impacting the serotonin receptors in the brain, helping to ease the mind before bedtime. This can be particularly beneficial for those who suffer from stress or anxiety-induced insomnia. Linalool’s analgesic properties help to alleviate pain, making it easier to fall asleep and stay asleep. Its anti-inflammatory effects also contribute to its ability to promote relaxation and comfort, further enhancing sleep quality.
3. Caryophyllene: Stress Relief
Caryophyllene is notable for its ability to bind to cannabinoid receptors in the body, similar to THC. It has a spicy, peppery aroma and is found in strains such as Bubba Kush and GSC (formerly Girl Scout Cookies).
Effects on Sleep: Caryophyllene is effective in reducing stress, which can significantly enhance sleep quality. It interacts directly with the endocannabinoid system, specifically binding to the CB2 receptors, which play a role in regulating stress and pain. This makes caryophyllene particularly useful for those who experience stress-related insomnia. Its anti-inflammatory properties help manage chronic pain and inflammation, contributing to a more restful sleep by reducing discomfort. Caryophyllene’s unique interaction with cannabinoid receptors also supports overall emotional balance, further aiding in achieving a peaceful state conducive to sleep.

4. Terpinolene: Mild and Relaxing
Terpinolene, though less common, is effective for promoting sleep. It has a fresh, herbal scent with citrus and pine notes and is present in strains like Jack Herer and Chernobyl.
Effects on Sleep: Terpinolene provides a gentle calming effect without being overly sedative, making it suitable for those who need to unwind without feeling heavily drowsy. Its mild sedative effects help to quiet the mind and prepare the body for sleep. Terpinolene also has antioxidant properties, which may contribute to overall health and well-being, further supporting restful sleep. Its uplifting properties can help improve mood, reducing stress and preparing the mind for a peaceful night’s rest.
5. Humulene: Subtle and Soothing
Humulene has a subtle, earthy aroma with woody, herbal notes. This terpene is found in strains like White Widow and Headband.
Effects on Sleep: Humulene can act as an appetite suppressant, potentially preventing late-night snacking that might disrupt sleep patterns. Its anti-inflammatory properties reduce pain and discomfort, promoting better sleep by easing conditions such as arthritis or other inflammatory disorders. Additionally, humulene has been shown to have antibacterial properties, which might contribute to overall health and a sense of wellbeing, further supporting restful sleep. Its soothing effects can help create a relaxed state that is conducive to falling and staying asleep.
Choosing the Right Terpene-Rich Cannabis Strain
By learning about the effects of various cannabis terpenes, you can better determine which of the various strains that Mamedica offers will best meet your needs, with the advice of a specialist.
At Mamedica, we provide personalised consultations with our expert doctors, where we’ll develop a tailored treatment plan just for you.
During this initial assessment, our specialists will thoroughly understand your sleep and health concerns to ensure your medical cannabis treatment is seamless, safe, and effective. If you struggle with insomnia and would like to start your medical cannabis journey, you can check your eligibility here.